Clinical Research Organization
crobangladesh@gmail.com
+8801819251514
Field Trial of Avian Influenza and Newcastle Disease Virus Vaccine in Layer Chicken
H9N2 is the most common subtype of influenza viruses in chicken and causes great economic loss for the poultry industry. Human infections with avian influenza virus revealed that H9N2 is the gene donor for H7N9 and H10N8 viruses that are infecting humans too. Newcastle Disease is a severe, systemic, and fatal viral disease of poultry due to virulent strains of avian paramyxovirus type 1. Control of the disease is challenging in enzootic regions.
The combination Avian Influenza and Newcastle Disease Virus Vaccine is an inactivated vaccine containing Avian Influenza Type A virus subtype H9N2 and Newcastle Disease Virus (LaSota strain). It is indicated for active immunization of healthy chickens against Low Pathogenic Avian Infuenza (AI) H9N2 and Newcastle Disease.
A field trial to determine potency and efficacy of this vaccine in layer chicken was carried out by CRO Ltd. The subjects were divided into five groups. Three groups were for potency and efficacy study.One group was vaccinated with investigational vaccine, one group vaccinated with commercially available vaccine and the third group was control. There are two more groups for safety study. One group was vaccinated with investigational product and the other group was control.
Sponsor of this field trial was Incepta Vaccine Ltd. (Human & Animal Division), Bangladesh. The trial was inspected by Directorate General of Drug Administration. It is now commercialized in Bangladesh as GurdFlu Plus vet, which is recommended for broiler, sonali, layer and breeding stock for protection against Low Pathogenic Avian Infuenza (AI) H9N2 and Newcastle Disease.